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Home > Lab Tests > HLA-DSA(Donor Specific IgG Antibod),Class I&II(L) Test

HLA-DSA(Donor Specific IgG Antibod),Class I&II(L) Test

₹ 10920



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Frequently Asked Questions (FAQ's)

Class 1 antibodies are present on almost all nucleated cells in the body, while Class 2 antibodies are predominantly found on certain white blood cells called antigen-presenting cells. Both classes of antibodies serve as markers that help determine compatibility between individuals, especially when it comes to organ transplantation.

When you undergo a blood test and the results show that you have tested positive for HLA antibodies, it means that your immune system has produced specific proteins called human leukocyte antigens (HLA) antibodies. These antibodies are directed against the HLA molecules found on the surface of cells in your body.

The DSA blood test, also known as Donor Specific Antibody test, is a diagnostic tool used in transplant medicine. It helps identify the presence of antibodies that target specific human leukocyte antigens (HLA) in the blood.

When a person has HLA antibodies, their immune system recognizes the transplanted organ as foreign and launches an attack against it. This can result in rejection of the organ and potential failure of the transplant. Symptoms that may arise from this rejection process include fever, swelling or tenderness around the transplant site, decreased urine output, fatigue, weight gain, or difficulty breathing.

The good news is that the DSA blood test, used to detect HLA-specific antibodies, is generally not considered to be painful.

The DSA test is an important tool in assessing the compatibility between a potential organ donor and recipient. By detecting the presence of HLA antibodies, specifically Donor Specific IgG Antibodies, it helps determine if there is a risk of rejection during transplantation.

Queries about this test

#1 What is DSA in HLA?

Ans: By identifying DSA in HLA, medical professionals can better evaluate the risk of rejection and tailor treatment plans accordingly. This helps improve outcomes for patients undergoing organ transplants.

#2 HLA and DSA the same?

Ans: HLA, or human leukocyte antigens, are proteins found on the surface of cells in our body. They play a crucial role in identifying what is "self" and what is "foreign" to the immune system. On the other hand, DSA stands for donor-specific antibodies. These antibodies are produced by the recipient's immune system in response to foreign HLA proteins from a transplanted organ.

#3 Positive DSA means

Ans: Positive DSA means that the individual has antibodies present in their blood that specifically target and recognize HLA molecules. These antibodies can potentially lead to complications in organ transplantation, as they can cause rejection of the donated organ.

#4 Normal range of DSA

Ans: It is important to note that there isn't a specific universally accepted standard for DSA levels as it can vary depending on factors such as age, gender, and overall health.

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