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Double Marker Test

Also Known as: Dual Marker Test, Double Marker Test in Pregnancy, First Trimester Screening
Downs Syndrome Risk(T21)
Pataus Syndrome Risk(T13)
+1 More
₹ 2350



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Description -

The Double marker test is conducted in the first trimester of pregnancy and helps determine if the foetus has a risk of developing some kind of chromosomal abnormality. Generally, this test is prescribed for pregnant women who are older than 35 years of age.

Overview of the Double Marker Test

A double marker test is done during pregnancy to identify any neurological disorders in the baby. It is a predictive test that is a part of the first-trimester screening to find out if there are any abnormalities in the chromosomes that can affect the baby’s growth.

It is crucial to conduct this test in the first trimester to identify Down syndrome or Edward’s syndrome in the baby. This test is used to check two markers: free beta HCG and PAPPA-A. The dual marker blood test only identifies the risk but does not confirm any abnormalities.

When the test result of the double marker test is under normal value, it means that there are no irregularities in the foetus's development. A screen negative is considered normal and indicates that the baby’s risk of having chromosomal abnormalities is low.

When is the Double Marker test prescribed?

The double marker test is conducted during pregnancy to determine if the unborn child has a risk of any kind of neurological disorders like Down’s syndrome, etc. Generally, this test is prescribed when the age of pregnant women is above 35 years, as this is the time when the risk of the foetus developing chromosomal abnormalities is higher.

This test needs to be conducted within a specific time window, between the 8th and 14th weeks of gestation. As the name suggests, this test is used to check two markers:

  • Free Beta HCG
  • PAPP-A (Pregnancy Associated Plasma Protein)

Frequently Asked Questions (FAQ's)

A double or dual marker test screening is conducted during the first trimester of pregnancy. It is a part of a full-fledged screening panel that is conducted between the 8th and 14th weeks of gestation. The purpose of a double marker test is to detect neurological abnormalities in the foetus. The results of this blood test are given in the form of ratios that you can correlate with the ranges provided in the report. “Screen positive” of a double marker test means that the foetus is in a high-risk zone while “screen negative” indicates that there are minimal or no risks involved. It is extremely essential that you choose a reputed lab to get these tests done for accurate results.

A Nuchal Translucency Scan or NT scan is an abdominal ultrasound, recommended for pregnant women between the 13th and 15th weeks of gestation. This ultrasound scan helps in detecting chromosomal abnormalities in the foetus. In the case of a double marker test, a blood sample is taken between the 8th and 14th weeks of gestation. This blood test also helps in detecting chromosomal abnormalities by measuring the levels of free beta hCG and Pregnancy Associated Plasma Protein (PAPP-A). An NT scan and a double marker test are done simultaneously in order to get a comprehensive screening during pregnancy. 

A double or dual marker test is prescribed to pregnant women during the first trimester of gestation. The main purpose of this blood test is to detect chromosomal abnormalities in the foetus. There is a very short window of time to get this test done in order to get the most accurate results. This period is between the 8th and 14th weeks of gestation. So, an OB/GYN will recommend a dual marker test in pregnancy during the end of the first trimester or the beginning of the second trimester. 

No, it is not possible to predict the gender of the foetus with a double marker test. This is because this blood test is conducted between the 8th and 14th weeks of gestation for determining chromosomal abnormalities. Not only is it difficult to know the gender during this period, but it is illegal to provide this information in India. So, pregnant women or their families cannot find out about the gender of the foetus with this blood test or any other screening test. Reputed pathologists, as well as medical practitioners, do not provide information about gender. 

When the test reports are provided to the patient, the results can either be “screen positive” or “screen negative”. A “screen positive” in a double marker test means that the foetus may be at a high risk of chromosomal abnormalities. In case there is a false-positive test result, then the chances of such neurological conditions may or may not be present upon birth. Since this blood test is conducted early on, parents can make a sound decision about the pregnancy based on the test results. 

A double market test helps in determining whether the foetus has neurological defects like Down syndrome, Edward’s syndrome, Patau’s syndrome, etc. When the report states “screen negative” in a double marker test, this means that the foetus is at low risk of chromosomal abnormalities. This means that the test results are in the normal range, so further testing will only be required if this is a family history or any other medical condition. 

No, the sample collection of a double marker test does not require fasting. So, there is no requirement for being empty stomach for this blood test. But if you feel any confusion regarding this, then it is best to contact Max Lab’s helpline before giving your blood sample. Another way to resolve this query is by speaking with a physician or OB/GYN in your city or town. 

The time taken to provide the report of a double marker test may vary between three days to a week. Max Lab ensures that the time duration of a double marker test report does not take more than two days after sample collection. Whether the test is conducted at a diagnostic centre of Max Lab or the sample is collected at your residence, the reports are provided on time. 


Double Marker Test Normal Range is 

Normal Range For Parameter Normal Ranges
Double Marker Test Risk  >1:1000

About This Test

The double marker test is carried out along with the NT scan, an ultrasound in which measurements are taken for the Nuchal fold of the foetus. The double marker test results are interpreted on the basis of these measurements.

The double marker test is a simple blood test and no specific preparations like fasting are required before sample collection.  The pregnant lady can eat or drink normally unless the doctor has instructed otherwise.

Time Required for Test Report and Next Steps

A person can check the double marker test price online and book the test. One just needs to search for a "double marker test near me" to know the location of the nearest Max Lab. Max Lab has an affordable dual-marker test price and gives reliable test results with 100% accuracy. The cost of a double-marker test at Max Lab is affordably priced. The person can opt for at-home blood sample collection. A phlebotomist comes for the blood sample collection for the double marker test and takes the sample to the laboratory where the test is performed.

The waiting time for a double marker test report is 3-4 days after sample collection. The double marker test results can be downloaded from the website, or one can collect them physically from the nearest Max Lab. One must take this test report to the doctor. He/she will suggest a proper course of action for further treatment.

Queries about this test

#1 Double Marker Test Negative Means

Ans: The phrase "screen negative" in a double marker test report denotes a low chance of chromosomal abnormalities for the fetus. It follows that the test findings fall within the expected range.

#2 Double Marker Test kab hota hai

Ans: इस ब्लड टेस्ट का प्राथमिक उद्देश्य विकासशील भ्रूण में अनुवांशिक विसंगतियों की तलाश करना है। सबसे सटीक निष्कर्ष प्राप्त करने के लिए यह समय सीमा गर्भावस्था के आठवें और चौदहवें सप्ताह के बीच है।

#3 Double Marker Test in Pregnancy

Ans: The double marker test is a basic blood test, and no special procedures, such as fasting before sample collection, are necessary. Unless the doctor has directed otherwise, the pregnant woman can eat and drink normally.

#4 Double Marker Test in which week

Ans: Between the eighth and fourteenth weeks of gestation, this blood test is performed to check for chromosomal anomalies.

#5 Double Marker Test in Hindi

Ans: गर्भावस्था के दौरान बच्चे में किसी भी न्यूरोलॉजिकल विकार की पहचान करने के लिए डबल मार्कर टेस्ट किया जाता है। यह एक प्रेडिक्टिव टेस्ट है जो पहली तिमाही की स्क्रीनिंग का एक हिस्सा है

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I am so happy that I can get the test done from Max Lab, and reports were available in within the day, and I don't have to wait a long time. The double marker test was a precautionary part of my pregnancy journey. The process was quick and smooth. Thanks, Max Lab!


I just wanted to say thank you Max Lab for providing me with such a quick and easy service for the Double Marker test. I had a pregnancy scare and needed to get tested. I was so happy to find out that the waiting time was not very long at all and that the test results were available online.


I am so glad I got the double marker test done from Max Lab as soon as I found out about my pregnancy. It was a relief to know there are no problems with the baby. Max Lab provided 100% accurate reports and they were available within 3-4 days of testing.

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