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The BCR-ABL test is used to measure the BCR-ABL protein level in the blood of a person. This protein mutation is formed when two genes are combined: BCR and ABL. The human body has BCR/ABL genes. However, if these genes mutate, it can cause certain blood disorders. The BCR-ABL test helps in the diagnosis of chronic myeloid leukaemia (CML). CML is a type of cancer that affects the blood cells and bone marrow of an individual.
Overview of the
The BCR-ABL test is used to measure the BCR-ABL protein level in the blood of a person. This protein mutation is formed when two genes are combined: BCR and ABL. The human body has BCR/ABL genes. However, if these genes mutate, it can cause certain blood disorders. The BCR-ABL test helps in the diagnosis of chronic myeloid leukaemia (CML). CML is a type of cancer that affects the blood cells and bone marrow of an individual.
BCR-ABL test is recommended by a doctor to an individual for the diagnosis of chronic myeloid leukaemia. This test finds the level of BCR-ABL in the blood. When these two genes switch places and make a new abnormal chromosome, it indicates the development of chronic myeloid leukaemia in the body. The cause of the development of CML is not known. There is no proven research proving that it comes from genetics or unhealthy habits. The only known risk is that individuals with high radiation exposure have a high chance of developing this disease. The doctor may recommend the BCR-ABL Qualitative test to find out the presence of a major or minor breakpoint. If the test result is positive, they may recommend the BCR-ABL PCR Quantitative test. If the BCR-ABL test report is negative, it rules out CML in a person.
....Read MoreThe BCR ABL test is a blood test that detects the presence of a genetic mutation known as the Philadelphia chromosome. This mutation causes chronic myeloid leukemia (CML), which is a type of cancer that affects your white blood cells.
The BCR ABL test is a critical diagnostic tool used to detect the presence of specific genetic abnormalities in individuals who may be at risk for certain types of cancer, including chronic myeloid leukemia and acute lymphoblastic leukemia. This test can help doctors determine if patients are candidates for targeted drug therapies that can effectively manage their condition.
There are different methods used to perform the BCR ABL test, including PCR (polymerase chain reaction) and FISH (fluorescence in situ hybridization). Both techniques amplify specific DNA sequences within cells to detect any abnormalities.
Determining who should get a BCR ABL test can be crucial in diagnosing certain types of leukemia. Typically, this test is recommended for people who have been experiencing symptoms that may indicate leukemia, such as unexplained weight loss, fatigue, fever and night sweats.
One of the most common is unexplained fatigue or weakness, which can be caused by anemia resulting from leukemia cells crowding out healthy blood cells. Another symptom is unexplained weight loss.
One thing you should keep in mind is that some medications can affect the accuracy of the results. Therefore, it is essential to inform your doctor about all the medications you are taking or if there have been any changes in your medication regimen recently.
However, this is a relatively safe and non-invasive procedure that carries very few risks.
During the test, a small sample of blood will be drawn from your arm. Some people may experience minor discomfort or bruising at the site where the needle was inserted, but these symptoms are usually mild and resolve quickly on their own.
The normal range for the BCR-ABL test varies depending on the laboratory where it is performed, but generally, a normal result falls within 0% - 1%.
The BCR-ABL test is used to measure the BCR-ABL protein level in the blood of a person. This protein mutation is formed when two genes are combined: BCR and ABL.
There are three phases of CML: chronic, accelerated, and blastic. The most common symptoms for each stage are:
Chronic Phase: The individual may not have any visible symptoms at this stage. This is the first stage of the disease.
Accelerated Phase:
Blastic Phase:
The doctor recommends a BCR-ABL blood test depending on the symptoms to diagnose CML. Also, they may suggest a complete blood count test, a bone marrow test, and an ultrasound to confirm the diagnosis.
When the BCR-ABL PCR test result is outside the normal range, it is one of the signs of CML in an individual. Other than this, the medical practitioner orders this test periodically to see the progress of treatment or signs of remission in an individual.
Max Lab offers the BCR-ABL test at a very affordable price so that people of any income level can afford proper healthcare services. We follow all the testing guidelines for the BCR-ABL test.
One can book the BCR-ABL test online at Max Lab's official website and schedule a visit from a phlebotomist for at-home sample collection. The phlebotomist visits on schedule for the blood sample collection. They are trained professionals who collect the blood sample in a sterilised container. The blood sample is carried to the Max Lab Centre, where the BCR-ABL test procedure is carried out. The individual can download their test report online or take a physical copy to the nearest Max Lab centre. The test report is generated within 24–48 hours of sample collection. After receiving your BCR-ABL test results, it is important to consult with a qualified doctor to understand the implications of the findings and get a proper line of treatment.
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