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Centromere Antibody Test

₹ 1400

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Test Name :	Centromere Antibody Test
Sample Type :	SERUM
Gender :	Both
Age group :	All Age Groups
This Test Includes :	Ab Centromere(CENP) 1 Tests

Price :

₹ 1400

Quick Summary: The Centromere Antibody is a diagnostic test, for both men and women across all age groups, with reports available within as per lab schedule — currently offered at ₹1400 . Home Sample Collection is available

Centromere Antibody Test Includes:
1 Tests Know More

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When is the Centromere Antibody Test Prescribed?
How to Interpret Centromere Antibody Test Results?
How To Prepare for the Centromere Antibody Test?

Description
The centromere antibody refers to an autoantibody, an abnormal protein generated by the body’s immune system that mistakenly attacks its own tissues. The Centromere Antibody test identifies and quantifies these antibodies in the bloodstream. It is primarily used as a diagnostic tool for systemic sclerosis (scleroderma), particularly one of its forms, by helping detect the p

The centromere antibody refers to an autoantibody, an abnormal protein generated by the body’s immune system that mistakenly attacks its own tissues. The Centromere Antibody test identifies and quantifies these antibodies in the bloodstream. It is primarily used as a diagnostic tool for systemic sclerosis (scleroderma), particularly one of its forms, by helping detect the presence of this immune-related activity in the body.

Centromere antibodies are immune system proteins associated with systemic sclerosis, an autoimmune condition that affects the skin, joints, and blood vessels. The purpose is to support diagnosis, differentiate systemic sclerosis from other autoimmune disorders with similar symptoms, and assist in monitoring disease progression and treatment response. Doctors typically order the Centromere Antibody test when investigating suspected systemic sclerosis (scleroderma). It is also helpful in distinguishing this condition from others presenting overlapping clinical features, especially when understanding the centromere antibody normal range and interpreting centromere antibody results.

Additionally, this test may be used when an ANA (antinuclear antibody) result comes back positive, particularly if the ANA pattern shows centromere, speckled, or nucleolar characteristics. In some cases, it is conducted alongside the Scl-70 (anti-topoisomerase) antibody test, another marker associated with scleroderma.

When is the Centromere Antibody Test Prescribed?

A healthcare provider may recommend this test when an individual has a positive ANA test, accompanied by symptoms characteristic of the CREST spectrum. These clinical signs include:

Calcinosis – presence of calcium deposits beneath the skin
Raynaud phenomenon – reduced blood circulation to fingers and toes, leading to colour changes such as white or blue
Oesophageal dysfunction – difficulty in swallowing, along with acid reflux and heartburn
Sclerodactyly – tight, thickened, and shiny skin over the fingers and hands
Telangiectasia – visible red spots on the skin caused by widened small blood vessels

How to Interpret Centromere Antibody Test Results?

When anticentromere antibodies (ACA) are detected in someone with CREST-related symptoms, it strongly suggests limited systemic sclerosis. In fact, ACA is seen in approximately 60–80% of individuals diagnosed with this form of the disease.

On the other hand, if ACA is not present, the symptoms are more likely linked to another medical condition. While uncommon, a small number of people with limited systemic sclerosis may not produce anticentromere antibodies, meaning the condition can still exist even when ACA results are negative.

How To Prepare for the Centromere Antibody Test?

No specific preparation is required for the Centromere Antibody test. Individuals can easily schedule the Centromere Antibody test through Max Lab at an affordable price, with the option for convenient home sample collection. Once the test is completed, the report is usually ready within 48 hours. It can be collected from the nearest Max Lab centre or downloaded directly from the official Max Lab website.

After receiving the test results, it is suggested to consult a healthcare professional. The doctor will review the report along with the individual’s medical history and symptoms to provide an accurate diagnosis. Based on the findings, the doctor may recommend a treatment plan or suggest additional tests if necessary.

About Centromere Antibody Test

The centromere antibody refers to an autoantibody, an abnormal protein generated by the body’s immune system that mistakenly attacks its own tissues. The Centromere Antibody test identifies and quantifies these antibodies in the bloodstream. When is the Centromere Antibody Test Prescribed? A healthcare provider may recommend this test when an individual has a positive ANA test, accompanied by symptoms characteristic of the CREST spectrum. These clinical signs include: Calcinos

When is the Centromere Antibody Test Prescribed?

A healthcare provider may recommend this test when an individual has a positive ANA test, accompanied by symptoms characteristic of the CREST spectrum. These clinical signs include:

Calcinosis – presence of calcium deposits beneath the skin
Raynaud phenomenon – reduced blood circulation to fingers and toes, leading to colour changes such as white or blue
Oesophageal dysfunction – difficulty in swallowing, along with acid reflux and heartburn
Sclerodactyly – tight, thickened, and shiny skin over the fingers and hands
Telangiectasia – visible red spots on the skin caused by widened small blood vessels

How to Interpret Centromere Antibody Test Results?

How To Prepare for the Centromere Antibody Test?

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Certified

Phlebotomist

🏥

Division of

Max Healthcare

🧪

Safe Sample

Collection

📊

Accurate &

Quality Reports

⏱️

Same Day

Report*

Trusted by

Professionals

When is the Centromere Antibody Test Prescribed?
How to Interpret Centromere Antibody Test Results?
How To Prepare for the Centromere Antibody Test?

When is the Centromere Antibody Test Prescribed?

A healthcare provider may recommend this test when an individual has a positive ANA test, accompanied by symptoms characteristic of the CREST spectrum. These clinical signs include:

Calcinosis – presence of calcium deposits beneath the skin
Raynaud phenomenon – reduced blood circulation to fingers and toes, leading to colour changes such as white or blue
Oesophageal dysfunction – difficulty in swallowing, along with acid reflux and heartburn
Sclerodactyly – tight, thickened, and shiny skin over the fingers and hands
Telangiectasia – visible red spots on the skin caused by widened small blood vessels

How to Interpret Centromere Antibody Test Results?

How To Prepare for the Centromere Antibody Test?

About Centromere Antibody Test

The centromere antibody refers to an autoantibody, an abnormal protein generated by the body’s immune system that mistakenly attacks its own tissues. The Centromere Antibody test identifies and quantifies these antibodies in the bloodstream. When is the Centromere Antibody Test Prescribed? A healthcare provider may recommend this test when an individual has a positive ANA test, accompanied by symptoms characteristic of the CREST spectrum. These clinical signs include: Calcinos

When is the Centromere Antibody Test Prescribed?

A healthcare provider may recommend this test when an individual has a positive ANA test, accompanied by symptoms characteristic of the CREST spectrum. These clinical signs include:

Calcinosis – presence of calcium deposits beneath the skin
Raynaud phenomenon – reduced blood circulation to fingers and toes, leading to colour changes such as white or blue
Oesophageal dysfunction – difficulty in swallowing, along with acid reflux and heartburn
Sclerodactyly – tight, thickened, and shiny skin over the fingers and hands
Telangiectasia – visible red spots on the skin caused by widened small blood vessels

How to Interpret Centromere Antibody Test Results?

How To Prepare for the Centromere Antibody Test?

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A normal anti-centromere antibody level is generally considered negative, meaning the antibody is not detected in the blood. A positive result indicates the presence of anticentromere antibodies, which may be associated with autoimmune conditions like systemic sclerosis. Reference ranges may vary based on the laboratory and testing method used.

The cost of an anti-centromere antibody test varies depending on the city, diagnostic laboratory, and whether home sample collection services are chosen. At Max Lab, the test typically costs around INR 1500.

Anti-centromere antibody is also known as the ACA test (Anticentromere Antibody Test).

Anti-centromere antibodies are most commonly associated with limited systemic sclerosis (CREST syndrome). They may also be seen in other autoimmune disorders, such as systemic lupus erythematosus, rheumatoid arthritis, and primary biliary cholangitis.

In CREST syndrome, the anticentromere antibody (ACA) is typically positive. This marker helps support diagnosis and differentiation from other forms of systemic sclerosis.

How to book a Centromere Antibody at home near me?

You can easily book a Centromere Antibody with Max Lab by Max Hospitals. Just follow these simple steps:

Search for Centromere Antibody near me on Google and click on the result with the Max Lab Website. OR Download the Max Lab App from Google Play Store or App Store.
Select Centromere Antibody from the "Book a test" button or search from the search bar on the website or Max Lab App.
Add other tests that you want to include with Centromere Antibody for home collection.
Choose a convenient date and time slot for sample collection.
A trained and certified phlebotomist will visit your preferred location — home or office — at the scheduled time to collect your blood sample safely.
You can also track your order at each step and view its status.
The sample will be processed at the nearest Max Hospital or Max Laboratory, and your test reports will be delivered within the specified time.
Track your health and past records with Max Lab's special feature that allows you to compare results with previous reports.

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