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Sample type :
TISSUE
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Description
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The IHC-MMR (Immunohistochemistry Mismatch Repair) test is a diagnostic tool used to assess the functionality of DNA mismatch repair proteins in tissues. By employing immunohistochemistry techniques to analyse colon and other tumour tissue, the MMR panel by IHC helps identify those who may be at risk for having certain types of cancer or Lynch Syndrome.
Overview of the Test
The M
The IHC-MMR (Immunohistochemistry Mismatch Repair) test is a diagnostic tool used to assess the functionality of DNA mismatch repair proteins in tissues. By employing immunohistochemistry techniques to analyse colon and other tumour tissue, the MMR panel by IHC helps identify those who may be at risk for having certain types of cancer or Lynch Syndrome.
The MMR panel by IHC is a staining test that is commonly used to help detect if there are any DNA mismatch repair proteins. While the immunohistochemistry test is a common test primarily used in the diagnosis of cancer, the immunohistochemistry MMR test is a specific test that helps identify hereditary or genetic mutations of proteins that may put a person at higher risk of Colorectal cancer (CRC) or Lynch Syndrome.
The IHC-MMR test allows visualisation of the proteins in the tissue, aiding in the identification of any deficiencies or abnormalities. An intact mismatch repair system has four proteins, and the absence of any one or more is considered a mutation in the gene. The procedure of the IHC-MMR test is a simple staining procedure, and only after an interpretation of the mismatch repair immunohistochemistry test results will a healthcare provider be able to prescribe appropriate treatment.
....Read MoreThe IHC-MMR (Immunohistochemistry Mismatch Repair) test is a diagnostic tool used to assess the functionality of DNA mismatch repair proteins in tissues.
The IHC-MMR test is commonly prescribed in cases where there is a suspicion of diseases which are associated with deficiencies in DNA mismatch repair proteins. Two of the main conditions include:
Additionally, the immunohistochemistry MMR test is valuable in assessing sporadic colorectal cancers, endometrial cancers, and other conditions where mismatch repair abnormalities may considered as a risk factor.
Individuals with a personal or family history of colorectal or endometrial cancers, especially those diagnosed at an early age, may also be prescribed the IHC-MMR test.
It is always advisable to choose a NABL-accredited diagnostic centre such as Max Lab to book the IHC-MMR test. One can visit the nearest Max Lab Centre or book the IHC-MMR test online by logging onto Max Lab’s website. The IHC-MMR test doesn’t have an at-home sample collection service since it needs a tissue sample collection.
After collection of the test sample, the report usually takes around 6 days to be generated, after which it can be downloaded online or collected in person. For an accurate interpretation of the ICH-MMR test results, it is highly recommended that one consult a medical professional. After a proper evaluation, one’s doctor will be able to suggest a further course of action and prescribe appropriate treatment.
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